Laboratory Surfactants and Wetting Agents
![Medchemexpress LLC 1-[(4-tert-butylphenyl)methyl]-3-[[3-fluoro-4-(methanesulfonamido)phenyl]methyl]thiourea | 401907-26-4 | MFCD29770787 | 99.5% | 423.57 g/mol | C20H26FN3O2S2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213556.png-250.jpg)
Medchemexpress LLC 1-[(4-tert-butylphenyl)methyl]-3-[[3-fluoro-4-(methanesulfonamido)phenyl]methyl]thiourea | 401907-26-4 | MFCD29770787 | 99.5% | 423.57 g/mol | C20H26FN3O2S2 | 5 MG
JYL 1421 is a potent transient receptor potential vanilloid 1 (TRPV1) antagonist used in preclinical research. It inhibits capsaicin-evoked intracellular Ca2+ accumulation in vitro (IC50 = 8 nM) and reduces capsaicin-induced behaviors in rodents (ID50 ≈ 4.6 mg/kg, i.p.). Supplied as a high-purity solid and as DMSO stock solutions for pharmacology and biochemical assays.
- Potent TRPV1 inhibition (IC50 = 8 nM).
- Blocks capsaicin-evoked Ca2+ accumulation in vitro.
- Demonstrated in vivo activity in rodent models (ID50 ≈ 4.6 mg/kg, i.p.).
- High purity suitable for research (>99%).
- Available as solid and as DMSO solution for convenient dosing.
![Medchemexpress LLC 3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-methanesulfonamidophenyl)methyl]thiourea | 401907-26-4 | MFCD29770787 | 99.5% | 423.57 g/mol | C20H26FN3O2S2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213385.png-250.jpg)
Medchemexpress LLC 3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-methanesulfonamidophenyl)methyl]thiourea | 401907-26-4 | MFCD29770787 | 99.5% | 423.57 g/mol | C20H26FN3O2S2 | 50 MG
JYL 1421 is a potent small-molecule antagonist of the transient receptor potential vanilloid 1 (TRPV1) channel, inhibiting capsaicin-evoked Ca2+ accumulation with an IC50 of 8 nM. Supplied for research use in solid form or as a 10 mM solution in DMSO, it is intended for in vitro pharmacology and calcium-flux studies.
- Potent TRPV1 antagonist (IC50 8 nM).
- High purity suitable for research use.
- Available as solid powder or 10 mM solution in DMSO.
- White to off-white powder appearance.
- Stable when stored as powder at -20°C for up to 3 years.
- Validated in capsaicin-evoked calcium accumulation assays.
Medchemexpress LLC Stachyose tetrahydrate | 10094-58-3 | 98.1% | 738.64 | 10 MG
Stachyose tetrahydrate is a natural saccharide, a tetrasaccharide composed of two α-D-galactose units, one D-glucose unit, and one D-fructose unit. This product appears as a white to yellow solid and is tested to comply with stringent specifications, ensuring high quality for various research applications.
- High purity: 98.10% by HPLC
- Appearance: White to yellow solid
- Recommended storage conditions: 4°C, sealed, away from moisture and light
- Long-term solvent storage: -80°C for 6 months or -20°C for 1 month in sealed, moisture and light-protected conditions
- Quality tested: Complies with specified standards
eMolecules 26530-26-7 | Medchem Express | KM04416 | 5mg | 779715174 | HY-148685 | MFCD00097921 | 249.28 | C12H11NO3S
Ambeed | (E)-4455-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-132-dioxaborolane | 250mg | 660584824 | A630869 | 642066-70-4 | 268.160 | C14H25BO4
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Selleck Chemical LLC CHAPS
CHAPS is a zwitterionic surfactant that decreases the sequence specificity of the nucleosome
Sigma Aldrich Fine Chemicals Biosciences CHAPS MOLECULAR BIOLOGY GRADE
NC3833143 CHAPS MOLECULAR BIOLOGY GRADE
Medchemexpress LLC L-372662 | 162045-26-3 | C33H38N4O6 | 50 MG
L-372662 is a potent and orally active non-peptide oxytocin antagonist. It exhibits selectivity to OTR:V1aR and has a Ki value of 4.8 for oxytocin. This compound demonstrates oral bioavailability with 90% in dogs and aqueous solubility of 10 mg/mL.
- Potent and orally active non-peptide oxytocin antagonist
- Ki value of 4.8 for oxytocin
- Exhibits selectivity to OTR:V1aR
- Demonstrates oral bioavailability (F = 90% in dogs)
- Aqueous solubility of 10 mg/mL
![Alkali Scientific CHAPS [3 [(3 Cholamidopropyl) dimethylammonio] 1 propanesulfonate], 100 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660376.jpg-250.jpg)
Alkali Scientific CHAPS [3 [(3 Cholamidopropyl) dimethylammonio] 1 propanesulfonate], 100 Grams
CHAPS (3-[(3-Cholamidopropyl)dimethylammonio]propane sulfonate) is a zwitterionic detergent used for membrane protein solubilization, offering mild, efficient protein extraction while preserving protein function. This 100g formulation is ideal for applications in membrane protein studies, including purification, structural analysis, and biochemical assays. CHAPS is often preferred in techniques such as electrophoresis, chromatography, and crystallization due to its ability to stabilize proteins in their native state without disrupting their activity. It is frequently used in laboratory experiments requiring the extraction and solubilization of membrane-bound proteins, enzymes, and cellular components.
Crescent Chemical Co Inc GUANIDINE THIOCYANATE
Guanidine thiocyanate molecular biology grade DNase/RNase not detected. Suitable for the isolation of RNA. Size - 500G Storage Conditions - +15 °C TO +30 °C Catalog Number - 39577.02 CAS 593-84-0
AG Scientific Inc CHAPS, High Purity, 5 G
CHAPS is a zwitterionic detergent that is widely used in the protein purification process. As part of this class of detergents, CHAPS contains both a positive and a negative group, but does not have a net overall charge. CHAPS has a relatively low biomembrane affinity, but is effective in inducing hemolysis and protein solubilization within specific concentration ranges. CHAPS is classified as a non-denaturing surfactant with a critical micelle concentration of 6-10mM.ApplicationsIn the laboratory, CHAPS and other zwitterionic detergents can be used for inducing cell lysis prior to protein isolation.CAS Number: 75621-03-03Molecular Weight: 614.9Chemical Formula: C32H58N2O7SSolubility: Soluble in DMSO or DMFStorage Temperature: Room TemperatureResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC CHAPS hydrate | 331717-45-4 | MFCD00078235 | C32H60N2O8S | 1 G
CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. It exhibits properties of weak cationic or nonionic surfactants, undergoing micellization and forming small, loose hydrophilic aggregates. It is commonly used in research for the separation and purification of membrane proteins.
- Stabilizes mononucleosomes
- Reduces nucleosome sequence specificity
- Promotes sliding of histone cores along DNA
- Solubilizes Tamm-Horsfall protein
- Maintains vesicle structure and related protein activity
- Used to recover native folded fusion proteins
- Enhances GST fusion protein binding capacity
- Restores GST enzyme activity